comparison of fecal calprotectin level in inflammatory bowel disease and irritable bowel syndrome

Inflammatory bowel disease or irritable bowel syndrome?

Gastrointestinal complaints are one of the most common reasons individuals seek medical care. Many have been through numerous physician consultations and treatment modalities without relief. Unfortunately, millions more suffer silently, thinking that their GI symptoms are “normal”; while self-medicating with antacids, Pepto Bismal or food avoidance. Additionally, many GI complaints are embarras...

Faecal calprotectin as a novel biomarker for differentiating between inflammatory bowel disease and irritable bowel syndrome.

The present study aimed to investigate faecal calprotectin as a diagnostic marker to differentiate between patients with inflammatory bowel disease (IBD) and those with irritable bowel syndrome (IBS). A total of 20 healthy control subjects, 26 patients with IBS and 58 patients with IBD, including 22 with ulcerative colitis (UC) and 36 with Crohn's disease (CD), were recruited for the present st...

Diets and Irritable Bowel Syndrome

Introduction: Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder, which is characterized by the presence of abdominal pain or discomfort associated with altered bowel habits. This systematic review aimed to assess the nutritional factors (dietary patterns and food groups) associated with IBS. Methods: Articles were collected ...

The Use of Fecal Calprotectin in Inflammatory Bowel Disease.

IB Calprotectin is a calciumand zinc-binding protein, which for practical purposes can be considered to be neutrophil-specific, although low levels are found in other phagocytic cells. Calprotectin accounts for approximately 60% of total soluble proteins in the cytosol fraction of neutrophils. Neutrophils are the common effector cells that define acute inflammation in response to a number of fa...

Fecal Lactoferrin Testing a Clinical Aid for Inflammatory Bowel Disease and Irritable Bowel Syndrome

Fecal lactoferrin in discriminating inflammatory bowel disease from Irritable bowel syndrome: a diagnostic meta-analysis

BACKGROUND To perform a meta-analysis evaluating the diagnostic ability of fecal lactoferrin (FL) to distinguish inflammatory bowel disease (IBD) from irritable bowel syndrome (IBS). METHODS The Medline, EMBASE, Web of Science, Cochrane library and CNKI databases were systematically searched for studies that used FL concentrations to distinguish between IBD and IBS. The sensitivity, specifici...